Everyone always asks me for recommendations on creams that will help with wrinkles. The ONLY topical creams ever proven to reduce wrinkles are prescription retinoids. Topical retinoids are a class of chemicals related to Vitamin A that increase the production of collagen in the skin. Retinoids treat fine lines, not deep wrinkles, and some discolorations caused by the sun. Anyone who can tolerate these creams should be using them. Unfortunately, unlike hair lasers or Latisse, the benefits of this treatment are more subtle and take months and more commonly years to manifest themselves. Some names are Renova, Refissa, generic tretinoin, Retin A, Differin, Tazorac, and TretinX.
The downside to retinoids can be significant, including redness, scaling and sometimes burning (so if you occasionally see me looking like a molting snake, you’ll know why). Therefore, it is important to find a strength and brand that works best for you, and you may not be able to apply it nightly, which is usually recommended. Moisturizers can also help somewhat with the scaling and irritation. Unfortunately, some women give up on retinoids due to these side effects. They will never be able to reap the long- term benefits that I see in women who have been using them for years.